CDC: Severe reactions to Moderna vaccine rare

Andrew Cummings
January 24, 2021

California chose to hold up the shipment of 330,000 doses earlier this week following a cluster of severe allergic reactions at one clinic that was administering the vaccine.

California's top epidemiologist late Wednesday said the Moderna vaccine suspected of causing a series of allergic reactions may be administered once again after a review found no reason to stop its use.

With the all-clear for Moderna's vaccine, San Francisco will be able to use 8,000 doses it had put on hold and no longer expects to run out of vaccine on Thursday as previously feared, the San Francisco Chronicle reported.

According to a report released by the US Centers for Disease Control and Prevention (CDC) on Friday, over 1,200 adverse events were reported after receipt of Moderna Covid-19 vaccine as of January 10, with 10 cases determined to be anaphylaxis.


No deaths were reported in adverse reactions. Pan said that all of the individuals who had reactions "are home and well".

The Moderna batch in question consists of roughly one million doses.

But without any studies, vaccine doses should not be mixed, said Naor Bar-Zeev, a vaccine expert at Johns Hopkins University.

"Yesterday, we convened the Western States Scientific Safety Review Workgroup and additional allergy and immunology specialists to examine the evidence collected", Pan said in a statement.


The new guidance stresses that "every effort" should be taken to ensure that a patient receives the same vaccine, but that "any available mRNA COVID-19 vaccine may be administered at a minimum interval of 28 days between doses" in certain unique circumstances such as available supplies being are limited or the patient being unaware of which vaccine they originally received.

Health officials reiterated that local medical staff should monitor inoculated patients for 15 minutes after vaccination, or 30 minutes for people with a history of immediate allergic reactions.

With early data proving the vaccine to be over 94.5% accurate, Moderna has quickly joined Pfizer among the front runners in the global race to contain COVID-19. But if only the opposite type of vaccine is available, the CDC said that the other vaccine can be administered and is considered effective.


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