Sputnik V Covid-19 vaccine gets nod for clinical trials in India

Henrietta Brewer
October 18, 2020

However, some recent global studies regarding mutations in the virus have raised concerns over its impact on the effectiveness of vaccines. The vaccine uses two adenovirus vectors (rAd26 and rAd5) against SARS-CoV-2 virus. It is to note that when a virus replicates, there may be some changes in the new strains that have formed.

He had also said the ICMR (Indian Council of Medical Research) was conducting large-scale sequencing of nationally representative strains collected over a few months and detailed results on mutations of the virus will be available in early October.

Andy Beshear announced that 1,295 new cases of COVID-19 were reported in Kentucky. He went on to suggest developing a vaccine delivery system on the lines of conduct of polls and disaster management while involving all levels of government and citizen groups.

However, whether the shot can safely protect people from the Covid-19 disease that has killed more than one million people worldwide will only become clear when final Phase III trials - which are ongoing outside China - are complete. At the same time, he also cautioned against any complacency at the decline and called for keeping up the efforts to contain the pandemic. "Practice social distancing, wear a face covering and practice good hand hygiene to reduce your chances of contracting COVID-19".

The Drug Controller General of India (DCGI) has granted approval to Dr Reddy's, a global pharmaceutical company headquartered in India, to conduct phase 2 and 3 clinical human trials of the Sputnik V, a Covid-19 vaccine made by Russian Federation.

Sputnik V vaccine, developed by Gamaleya National Research Institute of Epidemiology and Microbiology in Moscow, was registered by Russia's Ministry of Health of Russian Federation on August 11 to become the world's first registered vaccine against COVID-19.

"India is heading fast towards vaccine development as two manufacturers are already in phase-3 trial and one in the phase-2 trial, while more players are joining the race", the Indian Express quoted Jadhav as saying.

Sputnik, named after the world's first satellite launched by the erstwhile Soviet Union, is now a top vaccine contender along with those of AstraZeneca-Serum Institute of India, Bharat Biotech and Zydus Cadila that are undergoing clinical trials.

On September 16, RDIF reached an agreement with Dr Reddy's to conduct clinical trials and distribute 100 million doses of vaccine in India.

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