Potassium may help to prevent heart disease

Henrietta Brewer
October 10, 2017

Researchers have found that eating banana and an avocado can reduce the risk of heart problem as it prevents hardening of the arteries, it can also affect the result in heart problem and death.

Heart disease, which kills roughly 600,000 US citizens each year, is the leading cause of death for both men and women in the United States. It also assured that a person has a heart attack every 40 seconds, and more than a person dies from a heart disease each minute. They said the hardening of the arteries is significantly correlated to a diet based on potassium.

Through their analysis of cultured cross sections of mouse arteries and dietary experiments in live mice, the researchers confirmed that low potassium may lead to vascular calcification via calcium signaling, CREB, and autophagy.

Researches analyzed rats with high risks of heart attackts when given diet of high fat. While mice given high potassium diet experienced less artery hardening.

Working from living mice down to molecular events in cells in culture, the UAB researchers determined a causative link between reduced dietary potassium and vascular calcification in atherosclerosis, as well as uncovered the underlying pathogenic mechanisms. Then, these were split into three groups. They also help in moderating blood sugar level.

As a result, products that contain low levels of potassium have a negative effect on the rats ' health.

These effects suggest the transformation of VSMC into cells that possessed bone-like characteristics. They found that the low-potassium conditions promoted the expression of several gene markers that are hallmarks of bone cells, but decreased the expression of vascular smooth muscle cell markers, suggesting the transformation of the vascular smooth muscle cells into bone-like cells under low-potassium conditions. This was accompanied by activation of several known downstream mediators, including protein kinase C and the calcium-activated cAMP response element-binding protein, or CREB. The mice used were deficient in a protein called apolipoprotein E, which makes rodents more susceptible to atherosclerosis in response to a high-fat diet. Dietary potassium regulates vascular calcification and arterial stiffness.

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